Malignant Mesothelioma

Mesothelioma is cancer that occurs in the thin layer of tissue that covers most internal organs in the body. The type of mesothelioma is determined by what part is affected. The more common malignant pleural mesothelioma mostly affects the tissue that surrounds the lungs. The less common peritoneal/pericardial mesothelioma affects tissue in the abdomen, around the heart, and around the testicles. Many cases of mesothelioma are caused by occupational exposure to inhaled asbestos particles. Symptoms of mesothelioma can take 20-50 years to appear and include: trouble breathing, persistent cough, rib pain, swelling in the abdomen, fluid buildup in the lungs, unexpected weight loss, and anemia. There is currently no cure for mesothelioma, but treatment options focusing on enhancing prognosis include surgery, radiation therapy, chemotherapy, and targeted therapy. Biologic therapy using the patient’s immune system is currently being tested for its safety and efficacy.